Staphylococcal and Streptococcal Superantigen Exotoxins
نویسندگان
چکیده
منابع مشابه
A Multiplex Assay for Detection of Staphylococcal and Streptococcal Exotoxins
Staphylococcal and streptococcal exotoxins, also known as superantigens, mediate a range of diseases including toxic shock syndrome, and they exacerbate skin, pulmonary and systemic infections caused by these organisms. When present in food sources they can cause enteric effects commonly known as food poisoning. A rapid, sensitive assay for the toxins would enable testing of clinical samples an...
متن کاملPyrogenic specificity of streptococcal exotoxins, staphylococcal enterotoxin, and gram-negative endotoxin.
Streptococcal exotoxin and staphylococcal enterotoxin share several biological properties, including pyrogenicity, lymphocyte mitogenicity, and enhancement of gram-negative endotoxin lethality. These analogies of the toxins prompted comparative pyrogenic studies. When American Dutch rabbits were immunized by repeated intravenous injections of small amounts of staphylococcal enterotoxin, they ex...
متن کاملStaphylococcal scarlet fever: role of pyrogenic exotoxins.
Staphylococcal pyrogenic exotoxin (PE) types A and B were tested for their role in production of a scarlatiniform rash. The PEs elicited minimal skin reactions after intracutaneous injection into animals not presensitized to the toxins. In contrast, erythematous injection into animals not presensitized to the toxins. In contrast, erythematous and edematous rashes were produced after administrat...
متن کاملTranscytosis of Staphylococcal Superantigen Toxins
Staphylococcus aureus produces a set of proteins (e.g., staphylococcal enterotoxin A [SEA], SEB, toxic shock syndrome toxin 1 [TSST-1]) which act both as superantigens (SAgs) and toxins. Although their mode of action as SAgs is well understood, little is known about how they enter the body via the intestine and cause food poisoning. To examine this problem we used an in vitro culture system to ...
متن کاملStaphylococcal exotoxins induce interleukin 22 in human th22 cells.
BACKGROUND We have shown previously that T cells from atopic dermatitis (AD) patients produce more IL-22 upon staphylococcal exotoxin stimulation compared to psoriasis patients and healthy controls. The role of staphylococcal exotoxins on polarized memory T helper (Th)22 cells which are enriched in inflamed AD skin remains elusive. Our aim was to investigate IL-22 production in response to stap...
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ژورنال
عنوان ژورنال: Clinical Microbiology Reviews
سال: 2013
ISSN: 0893-8512,1098-6618
DOI: 10.1128/cmr.00104-12